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HeartGard Plus For Small Dogs – Blue Box

HeartGard Plus For Medium Dogs – Green Box

Heartgard Plus For Large Dogs - Brown Box

Heartgard Plus for Dogs – Monthly Heartworm Protection Made Easy

Heartworm disease can put your dog’s health at serious risk, and infected mosquitoes can be found across the United States. Give your dog a simple line of defense with Heartgard Plus for Dogs, a once-a-month, real-beef chew designed to help prevent heartworm disease.

More than heartworm prevention, Heartgard Plus also treats and controls three species of hookworms and two species of roundworms. Its tasty chew makes monthly protection easier to work into your dog’s routine, helping you stay on track with the parasite protection your furry family member needs.

Recommended For:

  • Puppies and Adult Dogs: Suitable for dogs from 6 weeks of age, when used as directed.
  • Dogs of Different Sizes: Available in weight-specific formulations for small, medium, and large dogs.

Important: Heartgard Plus is a prescription medication in the United States. Have your veterinarian test your dog for existing heartworm infection before starting prevention and confirm the appropriate product and dosage.

Heartgard Plus Coverage:

Heartgard Plus for Dogs provides monthly protection against heartworm disease while also treating and controlling common intestinal worms. Each monthly chew targets the following parasites:

  • Heartworms: Prevents canine heartworm disease by eliminating the tissue-stage larvae of Dirofilaria immitis for one month (30 days) after infection.

  • Roundworms: Treats and controls Toxocara canis and Toxascaris leonina.

  • Hookworms: Treats and controls Ancylostoma caninum, Uncinaria stenocephala, and Ancylostoma braziliense.

With one monthly chew, you can help protect your dog against heartworm disease while managing these specified intestinal parasites as part of your veterinarian-recommended prevention routine.

Directions

Giving Heartgard Plus for Dogs is simple when you follow the recommended monthly schedule.

  1. Give One Chew Each Month: Administer the prescribed chewable orally once every month, using the strength appropriate for your dog’s weight.

  2. Make Chew Time Easy: Offer it by hand or with a small amount of dog food. Encourage your dog to chew rather than swallow it whole. You can break it into pieces if your dog tends to swallow treats without chewing.

  3. Make Sure Your Dog Gets the Full Dose: Watch your dog for a few minutes after administration to ensure the entire dose is swallowed and not rejected. If any portion may have been lost, the product label recommends redosing.

  4. Keep Up With Monthly Prevention: Give each dose on schedule throughout the year, as directed by your veterinarian. Consistent monthly dosing is important for effective heartworm prevention.

Missed a Dose? Contact your veterinarian for guidance on restarting the monthly schedule, especially if multiple doses have been missed. Do not give extra doses without veterinary direction.

Storage Tip: Remove only one chewable from its foil-backed blister card at a time. Keep the remaining chewables in their original box to protect them from light.

  • Monthly Heartworm Prevention: Help protect your dog against heartworm disease with one chew every month, as directed by your veterinarian.

  • Protection Against Intestinal Worms: Heartgard Plus also treats and controls specified roundworms and hookworms.

  • Real-Beef Chew: Its real-beef formulation offers a convenient alternative to traditional tablets for dogs that prefer a chewable.

  • Easy Monthly Routine: A simple, recurring dose makes it easier to keep your dog’s parasite prevention on schedule.

  • Suitable for Young Puppies: Labeled for dogs and puppies 6 weeks of age and older, with no minimum weight requirement. Your veterinarian can confirm the appropriate dose for your puppy.

Heartgard Plus for Dogs combines two active ingredients, ivermectin and pyrantel, to provide monthly heartworm prevention and treatment and control of certain intestinal worms.

  • Ivermectin: Eliminates the tissue-stage larvae of Dirofilaria immitis, the parasite responsible for heartworm disease, helping prevent these larvae from developing into adult heartworms.

  • Pyrantel: Treats and controls specified intestinal roundworms and hookworms in dogs.

Together, these ingredients provide heartworm prevention alongside targeted protection against common intestinal worms when Heartgard Plus is administered monthly as directed.

Dog Size

Dog Weight

Pack Color

Ivermectin Strength

Pyrantel Strength

Chews per Month

Small Dogs

0–25 lbs

Blue

68 mcg

57 mg

1

Medium Dogs

26–50 lbs

Green

136 mcg

114 mg

1

Large Dogs

51–100 lbs

Brown

272 mcg

227 mg

1

For dogs weighing over 100 lbs: Use the appropriate combination of Heartgard Plus chewables to provide the recommended dose for your dog’s full body weight, as directed by your veterinarian.

Keep your dog protected by following these important precautions when using Heartgard Plus for Dogs.

  • Test Before Starting: Have your dog tested for existing heartworm infection before beginning prevention. Heartgard Plus does not kill adult heartworms. Dogs with an existing infection need appropriate veterinary treatment before starting a preventive program.

  • Follow the Age and Dosage Guidelines: Heartgard Plus is labeled for dogs and puppies 6 weeks of age and older. Use the chew strength appropriate for your dog’s weight and follow your veterinarian’s instructions.

  • Encourage Proper Chewing: Dogs that swallow treats whole should receive the chewable broken into pieces to reduce the risk of choking or intestinal obstruction. Watch your dog after administration to make sure the full dose is consumed.

  • Know What to Watch For: Report possible adverse reactions, such as vomiting, diarrhea, lethargy, loss of appetite, or unusual behavior, to your veterinarian.

  • Use During Pregnancy or Breeding: Heartgard Plus has demonstrated a wide safety margin at the recommended dose in pregnant and breeding dogs. Consult your veterinarian about its use for your dog.

  • Store Safely: Keep Heartgard Plus in its original box, protected from light, and out of reach of children and other animals. Store at 68°F–77°F (20°C–25°C); permitted temperature excursions are 59°F–86°F (15°C–30°C).

Important: Heartgard Plus is a prescription animal medication in the United States and should be used under veterinary direction.

1. What Is Heartgard Plus for Dogs?

Heartgard Plus is a monthly, real-beef-flavored chew that prevents canine heartworm disease and treats and controls two species of roundworms and three species of hookworms. It contains ivermectin and pyrantel.

2. How Do Dogs Get Heartworms?

Dogs get heartworms through the bite of an infected mosquito. The mosquito transmits infective heartworm larvae, which can develop into adult worms inside the dog. Regular preventive treatment helps stop these larvae from developing into adult heartworms.

3. At What Age Can Puppies Start Heartgard Plus?

Heartgard Plus is labeled for puppies and dogs 6 weeks of age and older. The appropriate chew strength depends on your dog’s weight. Ask your veterinarian when to begin prevention and confirm the correct dose.

4. Should Dogs Take Heartgard Plus All Year?

Many veterinarians recommend year-round heartworm prevention because mosquito exposure and heartworm risk can vary by location and season. Follow your veterinarian’s advice on maintaining uninterrupted prevention for your dog.

5. Does Heartgard Plus Kill Adult Heartworms?

No. Heartgard Plus prevents heartworm disease by eliminating the tissue-stage heartworm larvae targeted by the medication. It is not effective against adult heartworms. Dogs should be tested for existing heartworm infection before starting prevention, and infected dogs need veterinary treatment.

6. What Should I Know Before Giving Heartgard Plus to My Dog?

Have your dog tested for existing heartworm infection before starting treatment. Follow the weight-based dosing instructions, encourage your dog to chew the medication rather than swallow it whole, and discuss any health concerns or previous reactions to the ingredients with your veterinarian.

7. Can I Switch My Dog to Heartgard Plus From Another Heartworm Preventive?

Yes, a veterinarian can help you plan the transition. According to the product label, the first Heartgard Plus dose should be given within 30 days of the last dose of the previous heartworm preventive. Your veterinarian can advise on the appropriate timing for your dog’s circumstances.

8. What Should I Do If I Miss a Heartgard Plus Dose?

Give Heartgard Plus as soon as possible if a dose is delayed, then resume the recommended monthly schedule. Delays can reduce preventive effectiveness, so contact your veterinarian if more than 30 days have passed between doses or if you have missed multiple doses.

9. What Should I Do If My Dog Accidentally Receives Too Much Heartgard Plus?

Contact your veterinarian immediately if your dog receives more than the recommended dose. Have the product packaging and the amount given available so your veterinarian can assess the situation and advise you on the next steps.

10. What Heartgard Plus Sizes Are Available for Dogs?

Heartgard Plus comes in three weight-based strengths:

  • Blue: Small dogs weighing 0–25 lbs

  • Green: Medium dogs weighing 26–50 lbs

  • Brown: Large dogs weighing 51–100 lbs

Dogs weighing over 100 lbs require an appropriate combination of Chewables. Always choose the correct strength based on your dog’s weight and your veterinarian’s instructions.

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