Nexgard Chewables for Small Dogs – Orange Pack

Nexgard Chewables for Medium Dogs – Blue Pack

Nexgard Chewables for Large Dogs – Purple Pack

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Nexgard Chews for Extra Large Dogs – Red Pack

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NexGard for Dogs – Monthly Flea & Tick Protection

Fleas and ticks can make life uncomfortable for your dog and create ongoing problems around your home. NexGard for Dogs offers a convenient way to tackle these unwanted parasites with one beef-flavored chew every month. It kills adult fleas and helps prevent flea infestations while treating and controlling several common tick species.

Powered by afoxolaner, NexGard works systemically after administration, targeting fleas and ticks when they feed on your dog. It also helps prevent Borrelia burgdorferi infections by killing black-legged ticks that transmit Lyme disease. With four weight-based strengths and an easy-to-administer chewable format, NexGard makes monthly flea and tick protection easier to maintain.

Recommended For:

Puppies and Adult Dogs: Suitable for dogs and puppies 8 weeks of age and older.
Dogs of Different Sizes: Formulated for dogs weighing 4 lbs or more, with four weight-based chewable strengths.
Dogs Needing Monthly Flea and Tick Protection: Helps manage existing flea infestations and provides ongoing protection against specified tick species.
Dogs Exposed to Lyme Disease-Carrying Ticks: Helps prevent Borrelia burgdorferi infections by killing black-legged ticks.

NexGard Coverage:

NexGard provides monthly protection against fleas and treats and controls six species of ticks. Its active ingredient, afoxolaner, targets these external parasites after they feed on your dog.

Flea Protection:

Adult Fleas: Kills adult fleas (Ctenocephalides felis) and treats and prevents flea infestations.

Tick Protection:

Black-Legged Ticks: Treats and controls Ixodes scapularis infestations.
American Dog Ticks: Treats and controls Dermacentor variabilis infestations.
Lone Star Ticks: Treats and controls Amblyomma americanum infestations.
Gulf Coast Ticks: Treats and controls Amblyomma maculatum infestations.
Brown Dog Ticks: Treats and controls Rhipicephalus sanguineus infestations.
Longhorned Ticks: Treats and controls Haemaphysalis longicornis infestations.

Lyme Disease Prevention:

NexGard is also indicated for the prevention of Borrelia burgdorferi infections as a direct result of killing black-legged ticks (Ixodes scapularis), which transmit the bacteria responsible for Lyme disease.

Directions

NexGard Chews are designed for simple monthly administration. Follow these instructions to help ensure your dog receives the complete dose.

Choose the Correct Strength: Check your dog’s current weight and select the corresponding NexGard chewable strength.
Give the Chew Orally: Administer one chew by mouth once a month. NexGard can be given with or without food.
Ensure the Full Dose Is Consumed: Watch your dog after administration to make sure the entire chew has been eaten and no portion has been lost or refused.
Follow the Monthly Schedule: Repeat treatment every 30 days to maintain ongoing flea and tick protection.
Maintain Year-Round Protection: In areas where fleas are common throughout the year, continue monthly treatment without interruption.
Treat Other Household Pets: To help reduce the likelihood of flea reinfestation, use an approved flea control product for all susceptible animals in your household.

Missed a Dose? Administer NexGard when you remember and resume the regular monthly dosing schedule.

If Your Dog Vomits: If vomiting occurs within two hours of administration, or you suspect that some of the dose was lost, the product label instructs you to give another full dose.

Why Should You Buy NexGard?

Monthly Flea Protection: One convenient chew kills adult fleas and helps prevent flea infestations for one month.
Coverage Against Six Tick Species: Treats and controls six specified tick species, including black-legged, American dog, Lone Star, Gulf Coast, brown dog, and longhorned ticks.
Helps Prevent Lyme Disease: Indicated for the prevention of Borrelia burgdorferi infections by killing black-legged ticks that transmit the bacteria.
Fast-Acting Flea Treatment: Begins killing fleas within 4 hours of initial administration.
Beef-Flavored Chewable: An easy-to-administer oral treatment with a beef-flavored formulation.
Flexible Administration: Can be given with or without food, making it convenient to include in your dog’s routine.
Four Weight-Based Strengths: Available in different afoxolaner strengths to accommodate dogs of various sizes.

How Does NexGard Work?

NexGard Chews contain afoxolaner, an active ingredient belonging to the isoxazoline class of parasiticides. After your dog takes the chew, afoxolaner is absorbed into the bloodstream and distributed throughout the body.

When fleas and ticks feed on your dog, they ingest afoxolaner. The ingredient interferes with specific chloride channels in the parasites’ nervous systems, particularly those associated with GABA neurotransmission. This disrupts normal nerve activity, causing uncontrolled neurological activity, paralysis, and ultimately the death of the parasites.

NexGard begins killing fleas within 4 hours of initial administration and demonstrated greater than 99% effectiveness at 8 hours in a controlled laboratory study. Its systemic action also helps control the specified tick infestations over the monthly treatment period.

NexGard Dosing Guide:

NexGard is available in four strengths based on your dog’s body weight. Choose the appropriate chewable to provide the recommended afoxolaner dosage.

Dog Size	Dog Weight	Afoxolaner Strength	Chews Per Month
Small Dogs	4–10 lbs	11.3 mg	One
Medium Dogs	10.1–24 lbs	28.3 mg	One
Large Dogs	24.1–60 lbs	68 mg	One
Extra Large Dogs	60.1–121 lbs	136 mg	One

For dogs weighing over 121 lbs, administer the appropriate combination of NexGard Chews to provide the recommended dose.

Safety

Before starting NexGard for Dogs, review these precautions to help ensure appropriate use.

Age and Weight Requirements: NexGard is labeled for dogs and puppies 8 weeks of age and older, weighing at least 4 lbs.
Neurological Precautions: Afoxolaner belongs to the isoxazoline class, which has been associated with neurological adverse reactions, including muscle tremors, loss of coordination (ataxia), and seizures. Use caution in dogs with a history of seizures or neurological disorders. Seizures have also been reported in dogs without a previous seizure history.
Possible Side Effects: Reported adverse reactions include vomiting, dry or flaky skin, diarrhea, lethargy, and decreased appetite. Contact your veterinarian if your dog develops unusual symptoms after treatment.
Pregnant and Breeding Dogs: The safe use of NexGard in breeding, pregnant, or lactating dogs has not been evaluated. Consult your veterinarian before administration.
Follow the Recommended Dosage: Administer the chewable strength appropriate for your dog’s weight. Do not give additional doses unless instructed by your veterinarian.
Keep Away From Children and Other Animals: NexGard is intended for dogs only. Store it securely to prevent accidental ingestion or overdose by children, cats, or other pets.
Proper Storage: Keep NexGard in its original packaging and store at or below 86°F (30°C). Temperature excursions up to 104°F (40°C) are permitted.
Prescription Requirement: NexGard is a prescription animal medication in the United States and must be used under the direction of a licensed veterinarian.

Frequently Asked Questions (FAQs)

1. What Is NexGard for Dogs Used For?

NexGard is a beef-flavored chewable treatment used to kill adult fleas, treat and prevent flea infestations, and treat and control six specified tick species in dogs. It also helps prevent Borrelia burgdorferi infections as a direct result of killing black-legged ticks that transmit Lyme disease.

2. How Long Does NexGard Last in Dogs?

NexGard provides flea and tick treatment and control for one month per dose. To maintain continuous protection, administer the chewable once every month according to your veterinarian’s recommendations.

3. How Quickly Does NexGard Start Killing Fleas?

NexGard begins killing fleas within 4 hours of initial administration. In controlled laboratory studies, it demonstrated greater than 99% effectiveness at 8 hours. It works systemically, so fleas are exposed to afoxolaner when they feed on a treated dog.

4. At What Age Can Puppies Start Taking NexGard?

NexGard is labeled for puppies 8 weeks of age and older, provided they weigh at least 4 lbs. Both the minimum age and weight requirements must be met before starting treatment. Consult your veterinarian to confirm the appropriate chew strength.

5. Does NexGard Need to Be Given With Food?

No. NexGard can be administered with or without food. You can give the beef-flavored chew directly to your dog or offer it with a meal. Make sure your dog consumes the complete dose.

6. Does NexGard Prevent Lyme Disease in Dogs?

Yes. NexGard is indicated for the prevention of Borrelia burgdorferi infections as a direct result of killing black-legged ticks (Ixodes scapularis), which transmit Lyme disease. This is a specific product indication and does not mean NexGard prevents every tick-borne disease.

7. What Should I Do If My Dog Vomits After Taking NexGard?

If your dog vomits within two hours of receiving NexGard, the product label instructs you to administer another full dose. If vomiting occurs later, or your dog experiences repeated vomiting or other unusual symptoms, contact your veterinarian for advice.

8. What Happens If I Miss a NexGard Dose?

If you miss a scheduled dose, administer NexGard as soon as you remember and resume the regular monthly dosing schedule. Maintaining consistent monthly treatment helps avoid gaps in flea and tick protection.

9. Can NexGard Be Given to Dogs With a History of Seizures?

Use caution when administering NexGard to dogs with a history of seizures or neurological disorders. Afoxolaner belongs to the isoxazoline class, which has been associated with neurological adverse reactions, including tremors, ataxia, and seizures. Discuss your dog’s medical history with your veterinarian before treatment.

10. Is NexGard Safe for Pregnant or Nursing Dogs?

The safe use of NexGard in breeding, pregnant, or lactating dogs has not been evaluated. Consult your veterinarian before giving the medication to a dog that is pregnant, nursing, or intended for breeding.

11. Can NexGard Be Used With Other Medications?

In controlled field studies, NexGard was administered alongside commonly used medications, including vaccines, anthelmintics, antibiotics, steroids, NSAIDs, anesthetics, and antihistamines, without observed adverse reactions from their concomitant use. However, inform your veterinarian about all medications and supplements your dog takes before starting treatment.

12. Can NexGard Be Used With Other Flea and Tick Treatments?

Do not combine NexGard with another flea and tick medication without veterinary guidance. Some products may contain ingredients from the same isoxazoline class, and combining treatments can introduce unnecessary risks. Ask your veterinarian before using multiple parasite-control products together.

13. Does NexGard Protect Dogs Against Worms?

No. Regular NexGard Chews contain afoxolaner and target fleas and specified tick species. They do not provide heartworm or intestinal worm prevention. If your dog needs broader parasite protection, ask your veterinarian about an appropriate additional preventive.