Revolution Plus – All-in-One Protection for Cats

Revolution Plus is veterinarians’ #1 choice for cats according to Zoetis Pet Care. With over 25 years of proven protection of Revolution (selamectin), Revolution Plus offers broad-spectrum protection you can trust for your kittens and cats. This topical treatment for cats comes with a unique dual action formula (selamectin and sarolaner), meaning it is twice as tough on the parasites that cause harm and discomfort to your feline.

Revolution Plus once-monthly topical solution for cats comes in a quick-drying, small-volume and non-greasy single-use applicator for easy and mess-free application. It gives you the confidence of protecting your cats against the parasites that any cat or kitten regularly comes in contact with. Each dose effectively safeguards felines from fleas, flea tapeworms, ear mites, roundworms, hookworms and heartworm disease for one month. In addition, this all-in-one treatment for cats kills 4 types of ticks for a complete month with just one dose. Give your cats the much-needed inside-out protection in the form of convenient monthly spot-on Revolution Plus.

Recommended For:

Kittens & cats.
Revolution Plus is recommended for kittens and cats from 8 weeks of age and at least 2.8 lbs of body weight.

Revolution Plus Coverage:

Kills adult fleas.
Treats and prevents flea infestations.
Prevents tapeworm infections.
Prevents heartworm disease.
Treats and controls roundworm and hookworm infections.
Treats and controls ear mites.
Treats and controls tick infestations (lone star tick, Gulf Coast tick, American dog tick & black-legged tick).

Active Ingredients:

Selamectin, Sarolaner

Directions

Weigh your cat to select the suitable dosage.
Take the applicator tube out of the pack.
Puncture the seal of the tube by firmly pressing the cap down. A clicking sound will confirm that the seal is punctured.
Remove the cap and see whether the tip of the applicator tube is open.
Part the hair until the skin is visible on the cat’s back at the base of the neck between the shoulder blades.
Place the tip of the tube on the cat’s skin and squeeze it multiple times onto the skin in one spot to empty it.
Drag the tube away from the liquid, keeping it squeezed, and lift it to remove, ensuring that it is empty.
Avoid massaging the liquid into the skin after application.
For prevention of heartworm disease, administer Revolution Plus monthly year-round or at least within one month after your cat’s first exposure to mosquitoes and monthly afterwards until the end of the mosquito season.

Why Should You Buy Revolution Plus?

Comes with a unique dual-action formula that is twice as tough on parasites.
Provides broad-spectrum protection against internal & external pests.
Low-volume, quick-drying & non-greasy topical solution offers mess-free application without leaving oily residue on the cat.
A single dose protects against four tick species for a full month.
Ideal for cats living mixed lifestyles (indoor & outdoor).
Most prescribed parasite preventative for cats (according to the manufacturer).

How Does Revolution Plus work?

Revolution Plus combines two powerful active ingredients, selamectin and sarolaner. This combination provides a broader protection against both external and internal parasites with this dual-action formula.

Selamectin interferes with the glutamate-gated chloride channels, causing paralysis and death of the parasites, including roundworms, hookworms and heartworms. Sarolaner causes increased nerve stimulation in the parasites, such as fleas, ticks and ear mites and kills them. The unique bi-modal action of selamectin and sarolaner protects against fleas and ear mites for a complete month.

Revolution Plus began killing fleas within 12 hours of treatment and killed more than 98% of fleas within 24 hours, as per a laboratory study, stated in the product label. The label also indicates the onset of tick-killing activity within 24 hours of administration. The combination of selamectin and sarolaner is 100% effective in preventing the development of heartworms in cats infected with heartworm larvae (Dirofilaria immitis) 30 days before treatment, according to lab studies referenced in the label.

Revolution Plus Dosing Guide:

Cat Size	Cat Weight (lbs)	Pack Color	Tube Volume (ml)	Selamectin Strength (mg/tube)	Sarolaner Strength (mg/tube)	Doses Administered
Kittens & Small Cats	2.8 – 5.5	Yellow	0.25	15	2.5	One
Medium Cats	5.6 – 11.0	Orange	0.50	30	5.0	One
Large Cats	11.1 – 22.0	Green	1.00	60	10.0	One
For Cats over 22.0 lbs, administer the appropriate combination of Revolution Plus tubes.

Safety

Revolution Plus is not indicated for use in humans. You should keep these topical products out of the reach of children, uninformed people and pets. Do not allow children or anyone to come in contact with the application site until four hours after the application. Individuals with known hypersensitivity to any of the active ingredients should consult their healthcare professional before applying it to a cat.

This is a flammable treatment. Keep it away from heat, sparks, open flames or other sources of ignition. This topical treatment should be used with caution in cats with a history of seizures or neurologic disorders. Avoid applying it to broken skin. Do not apply it when the cat’s coat is wet.

The safe use of Revolution Plus has not been evaluated in kittens less than 8 weeks of age and pregnant, breeding or lactating cats. Field studies suggest that Revolution Plus can be used with other treatments, including vaccines, cestocidal anthelmintics, antibacterials, sedatives, anesthetics, opioid analgesics, corticosteroids, and NSAIDs.

Storage Guide:

Store at or below 30°C (86°F).

Frequently Asked Questions (FAQs)

Can I use Revolution Plus in a kitten younger than 8 weeks?

Revolution Plus is approved for use in kittens and cats 8 weeks of age and older, weighing at least 2.8 lbs. Do not apply it to kittens younger than 8 weeks.

When should I bathe my cat after using Revolution Plus?

There is no indication of bathing after treatment with Revolution Plus. It is, however, advisable to bathe and towel-dry the feline animal before applying the treatment. Talk to your vet for expert recommendations.

Should I test my cat for heartworm disease before switching to Revolution Plus?

Revolution Plus prevents the development of adult heartworms when administered to cats within 1 month of exposure to infective (L3) Dirofilaria immitis larvae. It eliminates the tissue stage of heartworm larvae for one month after infection.

Cats with a negative heartworm test before the initiation of Revolution Plus should be tested 3-4 months after initiating the treatment. Cats 6 months of age or older may be tested for heartworm infections before being treated with Revolution Plus.

How is Revolution Plus different from Revolution (selamectin)?

Revolution Plus contains an additional active ingredient in the form of sarolaner compared to Revolution (selamectin). This adds multiple tick coverage (lone star tick, Gulf Coast tick, American dog tick & black-legged tick) to Revolution Plus. In addition, the combination of sarolaner and selamectin provides a unique dual-action adulticide activity against fleas and ear mites. This formula broadens the coverage, including the most common parasites, such as fleas, flea tapeworms, ticks, ear mites, roundworms, hookworms, and heartworm disease.