Frontline Plus Flea & Tick Spot-On Treatment for Dogs

Fast-acting, waterproof monthly protection against fleas & ticks

Frontline Plus for Dogs is a trusted, vet-recommended topical flea and tick treatment designed to provide month-long protection against fleas, ticks, and chewing lice. This easy-to-apply spot-on solution works on contact, killing parasites before they can bite, while also breaking the flea life cycle to help prevent re-infestations.

Formulated with fipronil and (S)-methoprene, Frontline Plus offers reliable, waterproof protection for dogs of all sizes, including puppies from 8 weeks of age.

Key Benefits of Frontline Plus for Dogs

• Kills adult fleas and ticks on contact
• Eliminates flea eggs and larvae, breaking the flea life cycle
• Helps prevent flea allergy dermatitis (FAD)
• Effective against chewing lice
• Aids in the control of sarcoptic mange infestations
• Targets multiple tick species affecting dogs
• Helps reduce the risk of tick-borne diseases, including Lyme disease
• Easy-to-use monthly spot-on application
• Waterproof once dry (after 24 hours)

How Frontline Plus Works? (Veterinary Overview)

Frontline Plus combines two active ingredients:

• Fipronil – kills adult fleas, ticks, and chewing lice
• (S)-Methoprene – prevents flea eggs and larvae from developing

After application to the skin, the solution spreads across the body and concentrates in the sebaceous (oil) glands. These glands gradually release the medication over time, ensuring continuous protection—even if your dog gets wet after the product has dried.

Parasites do not need to bite to be killed; they are eliminated through direct contact with the treated skin and coat.

Frontline Plus Parasite Coverage

Frontline Plus is effective against:

Fleas

• Adult fleas
• Flea eggs
• Flea larvae

Ticks

• Brown dog ticks
• American dog ticks
• Lone star ticks
• Deer ticks

Other Parasites

• Chewing lice
• Sarcoptic mites (control)

How to Use Frontline Plus for Dogs

• Read all label instructions carefully before use.
• Ensure your dog is dry before application.
• Part the fur between the shoulder blades until the skin is visible.
• Remove the pipette from the blister pack and snap the tip.
• Apply the entire contents directly onto the skin in one spot.
• Allow the area to dry completely before contact.

* Do not bathe your dog or allow swimming for 24 hours after application.

Frontline Plus Dosage Chart

Do not exceed one application per dog per month.

Safety & Precautions

• For dogs only — do not use on cats, rabbits, or other animals
• Approved for dogs 8 weeks and older, weighing at least 5 lbs
• Keep children and pets away from the application site until dry
• Avoid touching the treated area until fully dry
• Wash hands thoroughly after application
• Do not eat, drink, or smoke while applying
• Consult a veterinarian before use in elderly, sick, or debilitated dogs
• If swallowed or if eye contact occurs, seek veterinary or medical advice immediately

Frequently Asked Questions (FAQs)

Q1. What is Frontline Plus for Dogs?

Frontline Plus is a topical flea and tick treatment that provides monthly protection against fleas, ticks, and chewing lice while also preventing flea egg and larval development.

Q2. How does Frontline Plus work?

After application, the active ingredients spread across the skin and coat and are stored in the skin’s oil glands, where they are slowly released to provide continuous protection—even after exposure to water.

Q3. How often should Frontline Plus be applied?

Frontline Plus should be applied once every month, preferably on the same date each month, for ongoing flea and tick control.

Q4. Can I use other flea or tick treatments with Frontline Plus?

No, Frontline Plus is designed to be used as a standalone flea and tick treatment. Using additional products may increase the risk of adverse effects.

Q5. How quickly does Frontline Plus start working?

Frontline Plus begins killing fleas, ticks, and chewing lice within a few hours of application.

Q6. Is Frontline Plus safe for dogs?

Yes, when used as directed, Frontline Plus is safe for dogs from 8 weeks of age and weighing at least 5 lbs, including pregnant, breeding, and lactating dogs.

Q7. Does Frontline Plus kill ear mites?

No, Frontline Plus is not intended for the treatment of ear mite infestations.

Product Information

Product Form: Topical Spot-On Solution

Target Species: Dogs

Active Ingredients: Fipronil, (S)-Methoprene

Shoppetcare Tip

For best results, use Frontline Plus every month year-round, especially in environments where fleas and ticks are common.